Adipose stem cell articles

Dr. Ricardo L. Rodriguez discusses Adipose stem cells and their use for plastic surgery.

  • Fat grafting to the breast – Will it affect mammograms?

    X-ray: Calcification from fat necrosis.

    Fat grafting, also known as fat transfers or fat injections, is a plastic surgery procedure which removes fat from unwanted areas of your body, carefully processes the fat, and then reinjects your own adipose fat tissue where more volume is desired. Fat injections can help rejuvenate your face, your buttocks, your hands, or your breasts. Fat injections are also being used in breast reconstruction surgery. Fat grafting will restore volume to the breast and can be performed with or without an implant. Lately we have seen some plastic surgery blogs expressing concern regarding how fat injections to the breast affect mammograms. We feel that both sides of the story are not being told, so we would like to address that here.

  • Stem cell summit: Adipose tissue has more stem cells than bone marrow

    Cover: New York stem cell summit '11.

    We attended Robin Young’s 6th annual Stem Cell Summit which was held this year on March 1st in New York City. Also in attendance were scores of public and private stem cell companies. Presentations included 21 adult stem cell companies, 3 embryonic companies, 7 device/instrumentation companies, and a panel of medical experts discussing Spinal Cord Injury. Each company gave a 10 to 15 minute presentation but we most enjoyed Dr. Arnold Caplan’s keynote address. Not only is he well known in academic circles, but he is no stranger to the biotech financial community, as he was the founder of Osiris Therapeutics (Nasdaq: OSIR), a publicly traded cell therapy company. Here are some highlights we took away from Caplan’s keynote speech entitled, The State of MSCs in 2011. If you are interested in stem cells from adipose tissue, you don’t want to miss this!

  • Stem cell niches, Stem cell activation, and Superman


    The Stem Cell Niche Stem cells usually exist in a low grade resting state in a controlled environment called a niche. The niche contains mesenchymal stem cells, also known as MSCs. The mesenchymal stem cell niche is usually located in the blood vessel wall itself. The status quo for a niche is not full blown stem cell activity, but a level of activity finely attuned to its surroundings. These cells like to keep a stable environment  (on the vessels) within the niche. They will only respond in a very specific way, to certain kinds of stimuli. In a chronic disease state such as scar tissue or aged skin, the stem cells present in that tissue are responding in many small and measured ways to whatever is happening in the tissue. Stem Cells are trying to maintain balanced conditions, this is called homeostasis. There are no big changes, just a low-grade adaptation to aging or scar process. This is why the stem cells in the local tissue are not doing what you would like them to do.

  • Plastic surgery predictions 2011: Fat stem cells 2.0

    A glowing crystal ball between 2 hands.

    2010 ushered in the new promising decade for the use of adipose stem cells. Stem cells from your own autologous fat, also known as adipose stem cells, have the power to rejuvenate tissue, heal wounds, and cure diseases. Taking the pulse at the various Stem Cell conferences around the country in 2010, we found that more clinical researchers are gravitating to adipose tissue as a source of stem cells. Bone marrow has historically been the default source of adult stem cells for researchers. Likewise, the volume of peer reviewed publications and research papers attesting to fat as an abundant source of stem cells has seen a tremendous increase in the past year. So what’s in store for 2011? Fat is phat again!

  • Centrifugation of fat tissue yields more stem cells than originally thought

    Lipid droplets.

    New evidence points to an improvement in vascularity and blood flow when stem cells are more concentrated in the fat to be transplanted. For therapeutic approaches, reproducible protocols of adipose-derived stem cells isolation and a large amount of cells are necessary, in order to respond to the increasing demand. Therefore, to practically understand what happens when adipose tissue is manipulated in the operating room, we studied the most common methods of fat processing employed by most plastic surgeons, in order to see which method yields the highest quantity of stem cells.

  • Fat injections to the face

    A side view photo of a female face with illustrations showing where the fat-injections will be applied.

    Fat grafts to the face are a great way to rejuvenate your face. As you age, your dermis thins, and your face will sag.You may lose volume in your cheeks and under your eyes. These areas appear to be hollow or not as defined as they were when you were younger. Additionally, some people have areas of their face lacking volume no matter what their age. Fat grafts will naturally fill those areas to restore your youthful appearance. Additionally, your own adipose fat contains adults stem cells. Adult stem cells have regenerative properties that can increase blood supply to your tissue and skin to make you look younger.

  • Cosmetic surgery trends for 2010 – Fat is phat!

    A glowing crystal ball between 2 hands.

    The year 2010 ushers in a new decade where science , beauty, and your own fat make a marriage that promises to deliver one of the most disruptive medical technologies of the century. Dr. Ricardo Rodriguez, a Yale trained Plastic Surgeon believes that stem cells from your own fat will lead the cosmetic surgery trends.

  • Recipe for permanent fat injections

    An illustration of the kitchen utensils needed for a recipe.

    Fat injections are long lasting if done correctly. That is my position and I stand by it! If you frequent various plastic surgery blogs, there is a big difference in the types of techniques that surgeons are using. Thus, there is a wide variation in their results, so many patients think that fat injections do not last. Fat injections are permanent if the following is done:

    1. correct technique of extraction and processing
    2. proper post surgical protocol for patient.
  • Lumpectomy reconstruction: fat grafts to the breast

    An illustration of a lumpectomy.

    An emerging alternative for breast reconstruction after lumpectomy with radiation is fat grafting to the breast. Fat grafting has been successfully performed for years, but the full healing powers of your own fat is a new frontier in Plastic Surgery. Read Dr. Rodriguez’s CosmeticSurg blog to find out more.

  • Stem cells from fat – Plastic surgery’s new frontier

    2 tubes of extracted fat.

    During the past decade, researchers have discovered that stem cells can also be extracted from your own fat tissue. These adult stem cells have the same potential as embryonic stem cells, except for the ability to differentiate into sperm or ova. Unlike embryonal stem cells, stem cells extracted from your own fat are abundant, easily available, and pose no ethical or political controversy.